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I would argue, after having chatted with doctors numerous times and hearing what I wanted to hear: No, Mom, you have to be exposed to a cold virus to catch a cold. Turns out we both were right, at least partially. You cant catch a cold without being exposed to a virus. Thats true enough. But a new study from Yale demonstrates cold viruses really dig chilling out. The Yale study, just published in the Proceedings of the National Academy of Sciences, helps reinforce what has been believed by most virologists since 1960. Viruses reproduce much more readily in nasal airways that have been chilled than when those airways are near normal body temperature. But this interdisciplinary Yale study focused more on how humans respond to the chill of veggiesensations winter, rather than the known viral response to the chill. Our immune systems fend with rhinoviruses at 37 degrees Celsius in nasal cavities (approximate body temperature) rather effectively compared to chilled air of 33 degrees Celsius in those passageways. Yale Professor of Immunobiology Akiko Iwasaki and her team found the immune response is actually impaired at the lower temperature. In mice, the study suggested once this thermal barrier is lowered, the virus can continue to replicate more rapidly even after core temperatures go back up to normal body temperatures.

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